Born in New York City; daughter of advertising executive Peter Griffith and Tippi Hedren, the cool blonde protagonist of Alfred Hitchcock's THE BIRDS (1963) and MARNIE (1964); educated at the Hollywood Professional School, CA. Griffith made her film debut as the promiscuous neglected daughter of an actress in Arthur Penn's NIGHT MOVES (1975). That same year, she was Miss Simi Valley in Michael Ritchie's SMILE (1975) before proceeding to specialize in playing precocious teens who were less innocent than they appeared. A hectic private life and well-publicized substance abuse problems hamstrung Griffith's Hollywood career as an adult until she cleaned up and starred as porn actress Holly Body in Brian De Palma's BODY DOUBLE (1984). Impressed by her work in De Palma's film, Jonathan Demme cast Griffith as Lulu/Audrey, the adventurous lead of SOMETHING WILD (1986). Mike Nichols' WORKING GIRL (1988) solidified her stardom and earned her a Best Actress nomination. Griffith has been busy ever since, starring in PACIFIC HEIGHTS and De Palma's ill-fated BONFIRE OF THE VANITIES (1990) before co-starring with then-husband Don Johnson in the romantic drama, PARADISE (1991). In 1992 Griffith endured two back-to-back failures as she attempted to expand her screen image. She failed to interest the public with her performances as a legal secretary turned WW II spy in SHINING THROUGH (1992) as well as the role of a tough NYC cop in love with a Hassidic Jewish man in Sidney Lumet's A STRANGER AMONG US (1992). She fell back upon her modern bombshell status to star in the remake of BORN YESTERDAY (1993) with Don Johnson and John Goodman. Other notable credits include MILK MONEY and NOBODY'S FOOL (both 1994), NOW AND THEN (1995), TWO MUCH and MULHOLLAND FALLS (both 1996), ANOTHER DAY IN PARADISE and LOLITA (both 1997), SHADOW OF DOUBT and CELEBRITY (both 1998), CRAZY IN ALABAMA and "RKO 281" (TV, as Marion Davies) (both 1999), CECIL B. DEMENTED and FOREVER LULU (both 2000), TART (2001), STUART LITTLE 2 (voice, 2002), THE NIGHT WE CALLED IT A DAY, SHADE and TEMPO (all 2003), and HAVE MERCY (2006). Griffith was married to Don Johnson twice, for six months in 1976, and from 1989 to 1996. She was married to actor Steven Bauer from 1981 to 1987. Since 1996, she has been married to actor Antonio Banderas.  Nominated for Best Performance by an Actress in a Leading Role 1988: WORKING GIRL 1 nomination